Late-stage functionalisation of alkyne-modified phospha-xanthene dyes: lysosomal imaging using an off–on–off type of pH probe
Journal article published in 2021 by
Hiroaki Ogasawara 
,
Yoshiki Tanaka,
Masayasu Taki ,
Shigehiro Yamaguchi
,
Yoshiki Tanaka,
Masayasu Taki ,
Shigehiro Yamaguchi
This paper is made freely available by the publisher.
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Abstract
A series of NIR-emissive phospha-xanthene dyes bearing an ethynyl group are reported. The late-stage functionalisation of the NIR dyes enables creation of multi-functionalised fluorescent probes that can be designed to target organelles of interest.