Published in
American Association for the Advancement of Science, Science Signaling, 687(14), 2021
DOI: 10.1126/scisignal.aba0717
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The costimulatory activity of Tim-3 requires Akt and MAPK signaling and its recruitment to the immune synapse
Journal article published in 2021 by
Shunsuke Kataoka 
,
Priyanka Manandhar,
Judong Lee,
Creg J. Workman ,
Hridesh Banerjee ,
Andrea L. Szymczak-Workman ,
Michael Kvorjak ,
Jason Lohmueller ,
Lawrence P. Kane
,
Priyanka Manandhar,
Judong Lee,
Creg J. Workman ,
Hridesh Banerjee ,
Andrea L. Szymczak-Workman ,
Michael Kvorjak ,
Jason Lohmueller ,
Lawrence P. Kane
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Abstract
The transmembrane receptor Tim-3 is recruited to the immune synapse of T cells, where it provides costimulatory signals.