This work is dedicated to the study of the spatio-temporal variability of climate in Morocco by the analysis of rainfall (gridded and gauged data) and runoff. The wavelet analysis method has been used in this study to compare the rainfall and runoff series and to show the major discontinuities identified in 1970, 1980, and 2000. Several modes of variability have been detected; this approach has been applied to show annual (1 year) and inter-annual modes (2–4 years, 4–8 years, 8–12/8–16 years, and 16–30 years), and some modes are specific to some stations. This analysis will be complemented by the gridded data covering the period from 1940 to 1999, which will allow for a better understanding of the spatial variability of the highlighted signals set, which identified frequencies at 1 year and 8–16 years, distinguished different time periods at each basin and identified three main discontinuities in 1970, 1980, and 2000. The contribution of climatic indices is important as it is between 55% and 80%.