Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade

Andrews, Miles C.; Duong, Connie P. M.; Gopalakrishnan, Vancheswaran; Iebba, Valerio; Chen, Wei-Shen; Khan, Md Abdul Wadud; Derosa, Lisa; White, Michael G.; Wong, Matthew C.; Ferrere, Gladys; Fluckiger, Aurélie; Roberti, Maria P.; Opolon, Paule; Alou, Maryam Tidjani; Roh, Whijae; Spencer, Christine N.; Curbelo, Irina Fernandez; Vence, Luis; Reuben, Alexandre; Johnson, Sarah; Wadud Khan, M. A.; Morad, Golnaz; Cooper, Zachary A.; Lastrapes, Matthew; Baruch, Erez N.; Prieto, Peter A.; Lazar, Alexander J.; Tetzlaff, Michael T.; Hudgens, Courtney W.; Cogdill, Alexandria P.; Gaudreau, Pierre-Olivier; Nezi, Luigi; Raoult, Didier; Yonekura, Satoru; Adamow, Matthew; Wargo, Jennifer A.; Haydu, Lauren E.; Routy, Bertrand; Tawbi, Hussein A.; Arora, Reetakshi; Hwu, Patrick; Mihalcioiu, Catalin; Hwu, Wen-Jen; Elkrief, Arielle; Little, Latasha; Amaria, Rodabe N.; Pezo, Rossanna C.; Gumbs, Curtis; Burton, Elizabeth M.; Woodman, Scott E.; Simon, Julie M.; Wani, Khalida; Diab, Adi; Patel, Sapna P.; Callahan, Margaret K.; Glitza, Isabella C.; Postow, Michael A.; Zhang, Jianhua; Ariyan, Charlotte E.; Ajami, Nadim J.; Petrosino, Joseph; Watowich, Stephanie; Tidjani Alou, Maryam; Jenq, Robert R.; Davies, Michael A.; Gershenwald, Jeffrey E.; Wong, Michael K.; McQuade, Jennifer; Sharma, Padmanee; Futreal, P. Andrew; Allison, James P.; Zitvogel, Laurence; Zhao, Li; Gardner, Julie

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Miles Andrews
Andrews et al., 2021

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Nature Research, Nature Medicine, 8(27), p. 1432-1441, 2021

DOI: 10.1038/s41591-021-01406-6

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@article{Andrews2021,
  author = {Andrews, Miles C. and Duong, Connie P. M. and Gopalakrishnan, Vancheswaran and Iebba, Valerio and Chen, Wei-Shen and Khan, Md Abdul Wadud and Derosa, Lisa and White, Michael G. and Wong, Matthew C. and Ferrere, Gladys and Fluckiger, Aurélie and Roberti, Maria P. and Opolon, Paule and Alou, Maryam Tidjani and Roh, Whijae and Spencer, Christine N. and Curbelo, Irina Fernandez and Vence, Luis and Reuben, Alexandre and Johnson, Sarah and Wadud Khan, M. A. and Morad, Golnaz and Cooper, Zachary A. and Lastrapes, Matthew and Baruch, Erez N. and Prieto, Peter A. and Lazar, Alexander J. and Tetzlaff, Michael T. and Hudgens, Courtney W. and Cogdill, Alexandria P. and Gaudreau, Pierre-Olivier and Nezi, Luigi and Raoult, Didier and Yonekura, Satoru and Adamow, Matthew and Wargo, Jennifer A. and Haydu, Lauren E. and Routy, Bertrand and Tawbi, Hussein A. and Arora, Reetakshi and Hwu, Patrick and Mihalcioiu, Catalin and Hwu, Wen-Jen and Elkrief, Arielle and Little, Latasha and Amaria, Rodabe N. and Pezo, Rossanna C. and Gumbs, Curtis and Burton, Elizabeth M. and Woodman, Scott E. and Simon, Julie M. and Wani, Khalida and Diab, Adi and Patel, Sapna P. and Callahan, Margaret K. and Glitza, Isabella C. and Postow, Michael A. and Zhang, Jianhua and Ariyan, Charlotte E. and Ajami, Nadim J. and Petrosino, Joseph and Watowich, Stephanie and Tidjani Alou, Maryam and Jenq, Robert R. and Davies, Michael A. and Gershenwald, Jeffrey E. and Wong, Michael K. and McQuade, Jennifer and Sharma, Padmanee and Futreal, P. Andrew and Allison, James P. and Zitvogel, Laurence and Zhao, Li and Gardner, Julie},
  doi = {10.1038/s41591-021-01406-6},
  journal = {Nature Medicine},
  month = {jul},
  pages = {1432-1441},
  title = {Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade},
  url = {https://www.nature.com/articles/s41591-021-01406-6.pdf},
  volume = {27},
  year = {2021}
}

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