Published in
American Association for the Advancement of Science, Science Advances, 43(7), 2021
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Microglia become hypofunctional and release metalloproteases and tau seeds when phagocytosing live neurons with P301S tau aggregates
Journal article published in 2021 by
Jack H. Brelstaff 
,
Matthew Mason ,
Taxiarchis Katsinelos ,
William A. McEwan ,
Bernardino Ghetti,
Aviva M. Tolkovsky ,
Maria Grazia Spillantini
,
Matthew Mason ,
Taxiarchis Katsinelos ,
William A. McEwan ,
Bernardino Ghetti,
Aviva M. Tolkovsky ,
Maria Grazia Spillantini
This paper is made freely available by the publisher.
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Abstract
Microglia change their behavior when eating live neurons containing tau protein aggregates, a hallmark of Alzheimer’s disease.