A Generic, Scalable, and Rapid Time-Resolved Förster Resonance Energy Transfer-Based Assay for Antigen Detection—SARS-CoV-2 as a Proof of Concept
Journal article published in 2021 by
Juuso Rusanen 
,
Lauri Kareinen ,
Leonora Szirovicza ,
Hasan Uğurlu ,
Lev Levanov,
Anu Jääskeläinen ,
Maarit Ahava,
Satu Kurkela,
Kalle Saksela ,
Klaus Hedman ,
Olli Vapalahti,
Jussi Hepojoki
,
Lauri Kareinen ,
Leonora Szirovicza ,
Hasan Uğurlu ,
Lev Levanov,
Anu Jääskeläinen ,
Maarit Ahava,
Satu Kurkela,
Kalle Saksela ,
Klaus Hedman ,
Olli Vapalahti,
Jussi Hepojoki
This paper is made freely available by the publisher.
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Abstract
PCR is currently the gold standard for the diagnosis of many acute infections. While PCR and its variants are highly sensitive and specific, the time from sampling to results is measured in hours at best.