Introduction: The fight against cervical cancer stumbles against resistance to accepting vaccines. Vaccination hesitancy is a worldwide phenomenon. It seems this phenomenon is more amplified in Africa. With the advent of COVID 19, many conspiracy theories against all the vaccines have emanated from various quarters. Vaccination against Human Papilloma Virus is no exception to the current dynamics. A study on this topic was carried out in the Fako Division-Cameroon. Structural and individual reasons could explain vaccination hesitancy. Objective: The objective of this study is to attempt an explanation of why vaccination hesitancy has to do with poor uptake of cervical cancer vaccines. Methodology: a community-based cross-sectional study was carried out in some towns of the Fako Division – Cameroon from 5 to January 20, 2021. Paper-based questionnaires were administered only to those who consented to participate in this study. And chi-square test was estimated to establish the association between participant socioeconomic characteristics and cervical cancer vaccine hesitancy Results: A total of 250 consecutively enrolled participants were included in the study. Women with a high level of education will readily accept vaccination against cervical cancer. About 71% of our sample does not trust government decisions regarding judgments against cervical cancer. If given a choice between medical treatment and prayers, 62% of our studied population will prefer prayers. There is some degree of bias against female children in our community. Conclusion: Many components constitute vaccination hesitancy. The corruption of political elites, brainwashing of masses by the new type of churches, self-convictions, ignorance, lack of knowledge on CC, and gender bias are some. They all increase on structural causes: the colonial background and the low socioeconomic status of these countries.