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American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 1(66), 2022

DOI: 10.1128/aac.01748-21

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Inhibitor-Resistant Mutants Give Important Insights into Candida albicans ABC Transporter Cdr1 Substrate Specificity and Help Elucidate Efflux Pump Inhibition

Journal article published in 2022 by Masakazu Niimi, Kyoko Niimi, Koichi Tanabe, Richard D. Cannon ORCID, Erwin Lamping ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Overexpression of ATP-binding cassette (ABC) transporters is a major cause of drug resistance in fungal pathogens. Milbemycins, enniatin B, beauvericin, and FK506 are promising leads for broad-spectrum fungal multidrug efflux pump inhibitors.