Published in
American Society for Microbiology, Microbiology and Molecular Biology Reviews, 3(85), 2021
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Large Clostridial Toxins: Mechanisms and Roles in Disease
Journal article published in 2021 by
Kathleen E. Orrell 
,
Roman A. Melnyk
,
Roman A. Melnyk
This paper was not found in any repository, but could be made available legally by the author.
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Abstract
Large clostridial toxins (LCTs) are a family of bacterial exotoxins that infiltrate and destroy target cells. Members of the LCT family include Clostridioides difficile toxins TcdA and TcdB, Paeniclostridium sordellii toxins TcsL and TcsH, Clostridium novyi toxin TcnA, and Clostridium perfringens toxin TpeL.