Published in
American Association for the Advancement of Science, Science Immunology, 65(6), 2021
DOI: 10.1126/sciimmunol.abf7235
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XIAP restrains TNF-driven intestinal inflammation and dysbiosis by promoting innate immune responses of Paneth and dendritic cells
Journal article published in 2021 by
Adam Wahida 
,
Madeleine Müller ,
Andreas Hiergeist ,
Bastian Popper ,
Katja Steiger ,
Caterina Branca ,
Markus Tschurtschenthaler,
Thomas Engleitner,
Sainitin Donakonda ,
Jordy De Coninck,
Rupert Öllinger ,
Marie K. Pfautsch,
Nicole Müller,
Miguel Silva ,
Sinem Usluer
and other authors.
,
Madeleine Müller ,
Andreas Hiergeist ,
Bastian Popper ,
Katja Steiger ,
Caterina Branca ,
Markus Tschurtschenthaler,
Thomas Engleitner,
Sainitin Donakonda ,
Jordy De Coninck,
Rupert Öllinger ,
Marie K. Pfautsch,
Nicole Müller,
Miguel Silva ,
Sinem Usluer
and other authors.
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Abstract
In XIAP deficiency, ileitis is driven by TNFR1- and TNFR2-dependent targeting of TLR5-expressing Paneth and dendritic cells.