ABSTRACT Objective to understand access to vaccination and its organizational aspects in the daily routine of Primary Health Care from users’s point of view. Method a holistic-qualitative multiple case study based on Comprehensive Sociology of Everyday Life, with 74 users from four sanitary microregions of the West Minas Gerais Extended Health Region, Brazil. As evidence data sources, we used the open and intensive individual interview, guided by a semi-structured script and technical visit to the vaccine rooms. Data were collected between June 2016 and April 2017. Data analysis was based on thematic content analysis. Results proved to be obstacles that compromise access to immunization services such as: the establishment of specific days for the performance of certain vaccines; the opening hours of vaccine rooms; lack of immunobiological; lack of guidance on the part of health professionals. It was evidenced that direct contact and insertion of users in other actions and services of the unit favor access to vaccination. A schedule for better access was suggested by users, who recommended: the reorganization of the days and times available for vaccination; vaccine card computerization; implementation of dissemination strategies to expand search for immunization; vaccination room structural adequacy; expansion of human resources in health units. Conclusion it is emphasized the importance of services identifying their weaknesses and adopting strategies that enable user-centered care, promoting access to health services and, consequently, immunization.