Published in

American Association for the Advancement of Science, Science Advances, 46(7), 2021

DOI: 10.1126/sciadv.abi8602

Links

Tools

Export citation

Search in Google Scholar

Lactate supports a metabolic-epigenetic link in macrophage polarization

Journal article published in 2021 by Jordan T. Noe ORCID, Beatriz E. Rendon ORCID, Anne E. Geller ORCID, Lindsey R. Conroy, Samantha M. Morrissey ORCID, Lyndsay E. A. Young ORCID, Ronald C. Bruntz, Eun J. Kim, Ashley Wise-Mitchell ORCID, Mariana Barbosa de Souza Rizzo ORCID, Eric R. Relich ORCID, Becca V. Baby ORCID, Lance A. Johnson, Hayley C. Affronti ORCID, Kelly M. McMasters and other authors.
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

Full text: Download

Green circle
Preprint: archiving allowed
Upload
Red circle
Postprint: archiving forbidden
Green circle
Published version: archiving allowed
Upload
Policy details
Data provided by SHERPA/RoMEO

Abstract

Macrophages use mitochondrial lactate metabolism for ACLY-dependent histone acetylation, immune suppression, and tumor progression.