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American Association for the Advancement of Science, Science Advances, 52(7), 2021

DOI: 10.1126/sciadv.abl3858

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Methylome inheritance and enhancer dememorization reset an epigenetic gate safeguarding embryonic programs

Journal article published in 2021 by Xiaotong Wu ORCID, Hongmei Zhang ORCID, Bingjie Zhang ORCID, Yu Zhang ORCID, Qiuyan Wang ORCID, Weimin Shen, Xi Wu, Lijia Li, Weikun Xia ORCID, Ryohei Nakamura ORCID, Bofeng Liu ORCID, Feng Liu ORCID, Hiroyuki Takeda ORCID, Anming Meng ORCID, Wei Xie ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Enhancer dememorization resets developmental clock and may unify epigenetic reprogramming modes in mammals and nonmammals.