Unintentional ingestion of a high dose of acenocoumarol in a young child
Journal article published in 2021 by
Martijn R. Brands 
,
Jelmer Sytema ,
Marinus van Hulst ,
Arvid Wa Kamps
,
Jelmer Sytema ,
Marinus van Hulst ,
Arvid Wa Kamps
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Abstract
Acute intoxication with a vitamin K antagonist may cause serious coagulopathy. We report the accidental ingestion of a high dose of acenocoumarol in a young child. Two intravenous administrations of 5 mg of vitamin K, in combination with fast and repeated administration of activated charcoal and sodium sulfate, were sufficient to prevent coagulopathy and related symptoms, despite a confirmed elevated blood acenocoumarol concentration (260 µg/L).