Published in
American Society for Microbiology, Infection and Immunity, 11(89), 2021
DOI: 10.1128/iai.00246-21
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Examining the Distribution and Impact of Single-Nucleotide Polymorphisms in the Capsular Locus of Streptococcus pneumoniae Serotype 19A
Journal article published in 2021 by
D. W. Arends 
,
W. R. Miellet,
J. D. Langereis ,
T. H. A. Ederveen,
C. E. van der Gaast–de Jongh,
M. van Scherpenzeel,
M. J. Knol,
N. M. van Sorge,
D. J. Lefeber,
K. Trzciński,
E. A. M. Sanders,
H. C. Dorfmueller ,
H. J. Bootsma,
M. I. de Jonge
,
W. R. Miellet,
J. D. Langereis ,
T. H. A. Ederveen,
C. E. van der Gaast–de Jongh,
M. van Scherpenzeel,
M. J. Knol,
N. M. van Sorge,
D. J. Lefeber,
K. Trzciński,
E. A. M. Sanders,
H. C. Dorfmueller ,
H. J. Bootsma,
M. I. de Jonge
This paper was not found in any repository, but could be made available legally by the author.
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Abstract
Streptococcus pneumoniae serotype 19A prevalence has increased after the implementation of the PCV7 and PCV10 vaccines. In this study, we have provided, with high accuracy, the genetic diversity of the 19A serotype in a cohort of Dutch invasive pneumococcal disease patients and asymptomatic carriers obtained in the period from 2004 to 2016.