The objective of this work was to evaluate the effects of splitting in three different doses of phosphorus and potassium, combined with each other, and it was applied fertirrigation in watermelon crop, and to evaluate their effects on fruit quality. The statistical was in a complete randomized block design, and the treatments were arranged in a factorial scheme (3 x 3) in subdivided splits, resulting in 9 treatments with tree replications, totaling 27 plots in the experimental area. In the horizontal plots the three doses of phosphorus fertilization (100, 150 and 300 kg.ha-1 of P2O5) were randomly allocated, and in the subplots the three potassium doses (50, 100 and 200 kg.ha-1 of K2O), were applied in fertirrigation. The cultivar used was Crimson Sweet. Seventy-Six days after planting (DAP) the biochemical characteristics of watermelon fruits were evaluated: total soluble solids (TSS), total treatable acidity (TTA) and potential of hydrogen (pH). According to the results, it was verified that only the chemical value of the TSS fruits, presented significant statistical differences between the studied doses because of the different source of fertilization K and P increased the soluble solid contents, the content of reducing sugars, and decreased pH. It was observed the different doses of K and P did not influence in the fruit quality parameters when it was analyzed separated: TTA and pH but the TTA values are according to consumer market standards. The best doses in order to economy of fertilizer were (150 kg ha-1 de P2O5 e 50 kg ha-1 of K2O).