River freshwater contribution in the European Atlantic margin and its influence on the sea salinity field are analyzed. The impacts of using a new river discharge database as part of the freshwater forcing in a regional ocean model are assessed. Ocean model scenarios, based on the CMEMS (Copernicus Marine Environment Monitoring Service) operational IBI-MFC (Iberia Biscay Ireland Monitoring Forecasting Centre) model set-up, are run to test different (observed, modeled and climatological) river and coastal freshwater forcing configurations throughout 2018. The modelled salinity fields are validated, using as a reference all known available in-situ observational data sources. The IBI model application is proven to adequately simulate the regional salinity, and the scenarios showcase the effects of varying imposed river outflows. Some model improvement is achieved using the new forcing (i.e., better capture of salinity variability and more realistic simulation of baroclinic frontal structures linked to coastal and river freshwater buoyancy plumes). Major impacts are identified in areas with bigger river discharges (i.e., the French shelf or the northwestern Iberian coast). Instead, the Portuguese shelf or the Gulf of Cadiz are less impacted by changes in the imposed river inflows, and other dynamical factors in these areas play a major role in the configuration of the regional salinity.