Published in
American Society for Microbiology, Journal of Virology, 3(96), 2022
DOI: 10.1128/jvi.01973-21
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Are COVID-19 Vaccine Boosters Needed? The Science behind Boosters
Journal article published in 2021 by
Rachel M. Burckhardt 
,
John J. Dennehy ,
Leo L. M. Poon ,
Linda J. Saif ,
Lynn W. Enquist
,
John J. Dennehy ,
Leo L. M. Poon ,
Linda J. Saif ,
Lynn W. Enquist
This paper is made freely available by the publisher.
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Abstract
Waning vaccine-induced immunity coupled with the emergence of SARS-CoV-2 variants has led to increases in breakthrough infections, prompting consideration for vaccine booster doses. Boosters have been reported to be safe and increase SARS-CoV-2-specific neutralizing antibody levels, but how these doses impact the trajectory of the global pandemic and herd immunity is unknown.