Published in
American Association for the Advancement of Science, Science Translational Medicine, 618(13), 2021
DOI: 10.1126/scitranslmed.abd7695
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MEF2 is a key regulator of cognitive potential and confers resilience to neurodegeneration
Journal article published in 2021 by
Scarlett J. Barker 
,
Ravikiran M. Raju ,
Noah E. P. Milman ,
Jun Wang,
Jose Davila-Velderrain ,
Fatima Gunter-Rahman ,
Cameron C. Parro,
P. Lorenzo Bozzelli ,
Fatema Abdurrob ,
Karim Abdelaal ,
David A. Bennett ,
Manolis Kellis ,
Li-Huei Tsai
,
Ravikiran M. Raju ,
Noah E. P. Milman ,
Jun Wang,
Jose Davila-Velderrain ,
Fatima Gunter-Rahman ,
Cameron C. Parro,
P. Lorenzo Bozzelli ,
Fatema Abdurrob ,
Karim Abdelaal ,
David A. Bennett ,
Manolis Kellis ,
Li-Huei Tsai
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Abstract
Mef2 is induced after enrichment in mice, reduces disease-associated hyperexcitability, and is a feature of cognitive resilience in patients with AD.