Published in
American Society for Microbiology, Infection and Immunity, 12(89), 2021
DOI: 10.1128/iai.00309-21
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Loss of neutrophil homing to the periodontal tissues modulates the composition and disease potential of the oral microbiota.
Journal article published in 2021 by
A. Hashim,
A. Alsam,
M. A. Payne,
J. Aduse-Opoku,
M. A. Curtis 
,
S. Joseph
,
S. Joseph
This paper is made freely available by the publisher.
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Abstract
Periodontal disease is considered to arise from an imbalance in the interplay between the host and its commensal microbiota, characterized by inflammation, destructive periodontal bone loss, and a dysbiotic oral microbial community. The neutrophil is a key component of defense of the periodontium: defects in their number or efficacy of function predisposes individuals to development of periodontal disease.