Association Between Early Treatment with Tocilizumab and Mortality Among Critically Ill Patients with Covid-19

Gupta, Shruti; Wang, Wei; Zhou, Yan; Zhang, Jingjing; Williams, Aquino; Zhou, Amy M.; Wen, Huei Hsun; Wen, Yumeng; Yap, Ernie; Zhu, Denzel; Yunes, Milagros; Whalen, William; Wu, Benjamin; Wunderink, Richard G.; Zonies, David; Yang, Heather; Woo, Sang Hoon; Zerda, David De La; Willett, Duwayne L.; Weiner, Daniel E.; Wilson, Perry; Hayek, Salim S.; Mathews, Kusum S.; Melamed, Michal L.; Schenck, Edward J.; Finkel, Diana; Green, Adam; Mallappallil, Mary; Faugno, Anthony J.; Velez, Juan Carlos Q.; Shaefi, Shahzad; Parikh, Chirag R.; Charytan, David M.; Friedman, Allon N.; Redfern, Roberta E.; Short, Samuel A. P.; Correa, Simon; Pokharel, Kapil K.; Donnelly, John P.; Gershengorn, Hayley B.; Douin, David J.; Semler, Matthew W.; Hernán, Miguel A.; Leaf, David E.; Walther, Carl P.; Kopecky, Kathleen F.; Milligan, Gregory P.; McCullough, Peter A.; Nguyen, Thuy-Duyen; Krajewski, Megan L.; Shankar, Sidharth; Pannu, Ameeka; Valencia, Juan D.; Waikar, Sushrut S.; Kibbelaar, Zoe A.; Hart, Peter; Upadhyay, Shristi; Wang, W.; Vohra, Ishaan; Oyintayo, Ajiboye; Rachoin, Jean-Sebastien; Schorr, Christa A.; Shea, Lisa; Edmonston, Daniel L.; Mosher, Christopher L.; Shehata, Alexandre M.; Cohen, Zaza; Mehta, Bijal; Walters, Patricia; Go, Ronaldo C.; Rose, Keith M.; Lisk, Rebecca; Gupta, Mrigank S.; Kim, Ethan C.; Coca, Steven G.; Saha, Aparna; Soh, Howard; Leven, Emily A.; Ss, Hayek; Wang, Jing G.; Mosoyan, Gohar; Nadkarni, Girish N.; Pattharanitima, Pattharawin; Gallagher, Emily J.; Guirguis, John; Kapoor, Rajat; Meshberger, Christopher; Kelly, Katherine J.; Garibaldi, Brian T.; Corona-Villalobos, Celia P.; Menez, Steven; Malik, Rubab F.; Gautam, Samir C.; Mallappallil, Mary C.; Ouyang, Jie; John, Sabu; Melaku, Yohannes; Mohamed, Ibrahim; Puri, Isha; Thaxton, Mariah; Wagner, John; Nguyen, H. Bryant; Leonberg-Yoo, Amanda; Kashani, Kianoush; Tehranian, Shahrzad; Thomas, Leslie F.; Sirganagari, Dheeraj Reddy; Guru, Pramod K.; Rodriguez, Jesus; Shah, Jatan A.; Kumar, Princy N.; Lazarous, Deepa G.; Kassaye, Seble G.; Johns, Tanya S.; Mocerino, Ryan; Prudhvi, Kalyan; Levy, Rebecca V.; Fisher, Molly; Sedaliu, Kaltrina; Ks, Mathews; Golestaneh, Ladan; Kumar, Neelja; Thakkar, Jyotsana; Raichoudhury, Ritesh; Radbel, Jared; Farag, Mohamed; Cho, Soo Jung; Plataki, Maria; Gomez-Escobar, Luis G.; Pan, Di; Lee, Stefi; Krishnan, Jamuna; Macina, Ashley; Chaudhry, Sobaata; Reiser, Jochen; Modersitzki, Frank; Leidner, Alexander S.; Martinez, Carlos; Kruser, Jacqueline M.; Hodakowski, Alexander J.; Price-Haywood, Eboni G.; Ml, Melamed; Matute-Trochez, Luis A.; Hasty, Anna E.; Mohamed, Muner M.-B.; Sise, Meghan E.; Newman, Erik T.; Omar, Samah Abu; Sharma, Shreyak; Singh, Harkarandeep; Shaukat, Tanveer; Kamal, Omer; Lee, Meghan; Strohbehn, Ian A.; Li, Jiahua; Mueller, Ariel L.; Srivastava, Anand; Naimy, Gabriel; Hall, Danyell; Rowan, Chris; Madhani-Lovely, Farah; Peev, Vasil; Vissing, Andrew; Sk, Brenner; Kapania, Esha M.; Post, Zoe; Patel, Nilam P.; Hermes, Joy-Marie; Sutherland, Anne K.; Patrawalla, Amee; Finkel, Diana G.; Danek, Barbara A.; Paer, Jeffrey M.; Liotta, Mark; Puri, Sonika; Sunderram, Jag; Scharf, Matthew T.; Vatson, Jayanth S.; Levitt, Joseph E.; Garcia, Pablo; Song, Rui; Chan, Lili; Deng, Xiaoying; Katz-Greenberg, Goni; Senter, Katharine; Sharshir, Moh’d A.; Rusnak, Vadym V.; Peters, Terri; Hughes, Kathy; Podoll, Amber S.; Chonchol, Michel; Sharma, Sunita; Rashidi, Arash; Hejal, Rana; Judd, Eric; Latta, Laura; Tolwani, Ashita; Schulze, Carl E.; Macedo, Etienne; Rhee, Harin; Liu, Kathleen D.; Jotwani, Vasantha K.; Koyner, Jay L.; Shah, Chintan V.; Jaikaransingh, Vishal; Toth-Manikowski, Stephanie M.; Joo, Min J.; Lash, James P.; Ej, Schenck; Neyra, Javier A.; Elias, Madona; Iardino, Alfredo; Sharma, Jill H.; Sosa, Marie Anne; Taldone, Sabrina; Contreras, Gabriel; Fornoni, Alessia; Shadid, Husam; Pan, Michael; O’ Hayer, Patrick; Meloche, Chelsea; Feroze, Rafey; Padalia, Kishan J.; Leya, Jeff; Flythe, Jennifer E.; Tugman, Matthew J.; Leonberg-Yoo, Amanda K.; Spiardi, Ryan C.; Miano, Todd A.; Roche, Meaghan S.; Vasquez, Charles R.; Ernecoff, Natalie C.; Kapoor, Sanjana; Verma, Siddharth; Chen, Huiwen; Kovesdy, Csaba P.; Molnar, Miklos Z.; Hedayati, S. Susan; Nadamuni, Mridula V.; Shastri, Shani; Renaghan, Amanda D.; Enfield, Kyle B.; Malik, A. Bilal; Vijayan, Anitha; Joy, Christina Mariyam; Li, Tingting; Goldberg, Seth; Kao, Patricia F.; Schumaker, Greg L.; Goyal, Nitender; Hsu, Caroline M.; Tariq, Asma; Meyer, Leah; Kshirsagar, Ravi K.; Jose, Aju; Christov, Marta; Griffiths, Jennifer; Gupta, Sanjeev; Kapoor, Aromma; Ugwuowo, Ugochukwu; Brenner, Samantha K.; Bansal, Anip; Athavale, Ambarish M.; Admon, Andrew J.; Anumudu, Samaya J.; Arunthamakun, Justin; Allusson, Valerie; Bambrick-Santoyo, Gabriela; Bhatti, Noor ul aain; Altman, Deena R.; Bose, Sonali; Cervantes, Carmen Elena; Bajracharya, Siddhartha; Bhattacharya, Jyotsna; Boudourakis, Leon; Ahoubim, Afshin; Bergl, Paul A.; Azzi, Yorg; Brogan, Maureen; Chang, Michael; Athreya, Akshay; Alvarez-Mulett, Sergio L.; Avasare, Rupali S.; Boateng, Jeffery O.; Cairl, Nicholas S.; Abu-Saif, Abeer; Bickley, Laura; Byun, John J.; Arikapudi, Sowminya; Cangialosi, Peter; Ahmed, Ayesha; Bansal, Amar D.; Berim, Ilya; Anand, Shuchi; Boyle, Suzanne M.; Arif, Ali; Ali, Muhammad Imran; Burnham, Ellen L.; Charytan, David; Albertson, Timothy E.; Adams, Jason Y.; Chang, Steven Y.; Beutler, Rebecca M.; Chaaban, Nourhan; Ahmad, Yahya; Au, Elizabeth H.; Blakely, Pennelope; Berlin, Hanna; Azam, Tariq U.; Bitar, Abbas; Chang, Emily H.; Brown, Brent R.; Azhar, Ambreen; Bhatraju, Pavan K.; Arora, Tanima; Stop Covid, Investigators

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American Medical Association, JAMA Internal Medicine, 1(181), p. 41, 2021

DOI: 10.1001/jamainternmed.2020.6252

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Association Between Early Treatment with Tocilizumab and Mortality Among Critically Ill Patients with Covid-19

Journal article published in 2020 by Shruti Gupta, Wei Wang, Yan Zhou, Jingjing Zhang, Aquino Williams, Amy M. Zhou, Huei Hsun Wen, Yumeng Wen, Ernie Yap, Denzel Zhu, Milagros Yunes, William Whalen, Benjamin Wu, Richard G. Wunderink, David Zonies and other authors.

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Association Between Early Treatment with Tocilizumab and Mortality Among Critically Ill Patients with Covid-19