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American Society for Microbiology, mBio, 2(12), 2021

DOI: 10.1128/mbio.03681-20

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Multidisciplinary Approaches Identify Compounds that Bind to Human ACE2 or SARS-CoV-2 Spike Protein as Candidates to Block SARS-CoV-2–ACE2 Receptor Interactions

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

SARS-CoV-2, the causative agent of COVID-19, has caused more than 60 million cases worldwide with almost 1.5 million deaths as of November 2020. Repurposing existing drugs is the most rapid path to clinical intervention for emerging diseases.