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American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 11(65), 2021

DOI: 10.1128/aac.00988-21

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Evaluation of AT-752, a double prodrug of a guanosine nucleotide analog with in vitro and in vivo activity against dengue and other flaviviruses

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Every year, millions of people worldwide are infected with dengue virus (DENV), with a significant number developing severe life-threatening disease. There are currently no broadly indicated vaccines or therapeutics available for treatment of DENV infection.