Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B.1.1.7

Meng, Bo; Kemp, Steven A.; Papa, Guido; Datir, Rawlings; Ferreira, Isabella A. T. M.; Marelli, Sara; Harvey, William T.; Lytras, Spyros; Mohamed, Ahmed; Gallo, Giulia; Consortium, Covid-19 Genomics Uk (Cog-Uk); Thakur, Nazia; Collier, Dami A.; Mlcochova, Petra; O'Grady, Justin; Duncan, Lidia M.; Robson, Samuel Charles; Loman, Nicholas J.; Carabelli, Alessandro M.; Connor, Thomas R.; Golubchik, Tanya; Kenyon, Julia C.; Martinez Nunez, Rocio T.; Lever, Andrew M.; Ludden, Catherine; Corden, Sally; De Marco, Anna; Smith, Colin P.; Johnston, Ian; Bonsall, David; Saliba, Christian; Torok, M. Estee; Awan, Ali R.; Culap, Katja; Bucca, Giselda; Jackson, David K.; Cameroni, Elisabetta; Saeed, Kordo; Hamilton, William L.; Matheson, Nicholas J.; Prieto, Jacqui A.; Piccoli, Luca; Corti, Davide; Snell, Luke B.; James, Leo C.; Moore, Catherine; Nicholls, Sam; Robertson, David L.; Bull, Matthew; Harrison, Ewan M.; Bailey, Dalan; Goncalves, Sonia; Smith, Darren L.; Barrett, Jeff; Fairley, Derek J.; Gupta, Ravindra K.; Aanensen, David M.; Loose, Matthew W.; Curran, Martin D.; Watkins, Joanne; Parmar, Surendra; Livett, Rich; Aggarwal, Dinesh; Shepherd, James G.; Moses, Samuel; Parker, Matthew D.; Glaysher, Sharon; Amato, Roberto; Bashton, Matthew; Underwood, Anthony P.; Pacchiarini, Nicole; Templeton, Kate E.; Langford, Cordelia F.; de Silva, Thushan I.; Sillitoe, John; Wang, Dennis; Kwiatkowski, Dominic; Rambaut, Andrew; Loveson, Katie F.; O’Grady, Justin; Cottrell, Simon; Holden, Matthew T. G.; Thomson, Emma C.; Osman, Husam; Andersson, Monique; Hassan-Ibrahim, Mohammed O.; Lawniczak, Mara; Alderton, Alex; Chand, Meera; Constantinidou, Chrystala; Unnikrishnan, Meera; Darby, Alistair C.; Chauhan, Anoop J.; Hiscox, Julian A.; Paterson, Steve; Martincorena, Inigo; Volz, Erik M.; Page, Andrew J.; Pybus, Oliver G.; Bassett, Andrew R.; Chapman, Michael H. Spencer; Li, Kathy K.; Shah, Rajiv N.; Jesudason, Natasha G.; Taha, Yusri; McHugh, Martin P.; Dewar, Rebecca; Jahun, Aminu S.; O'Toole, Áine; McMurray, Claire; Young, Gregory R.; Ariani, Cristina V.; Pandey, Sarojini; McKenna, James P.; Nelson, Andrew; McCann, Clare M.; Elliott, Scott; Lowe, Hannah; Temperton, Ben; Wyles, Matthew; Roy, Sunando; Price, Anna; Rey, Sara; de Cesare, Mariateresa; Rooke, Stefan; Shaaban, Sharif; Letchford, Laura; Wilson-Davies, Eleri; Gramatopoulos, Dimitris; Silveira, Siona; Pelosi, Emanuela; Hosmillo, Myra; O’Toole, Áine; Hesketh, Andrew R.; du Plessis, Louis; Stark, Richard; Ruis, Chris; Adams, Helen; Michell, Stephen L.; Grammatopoulos, Dimitris; Edgeworth, Jonathan; Breuer, Judith; Todd, John A.; Bourgeois, Yann; Fraser, Christophe; Buck, David; John, Michaela; Kay, Gemma L.; Weldon, Danni; Peacock, Sharon J.; Heyburn, David; Robinson, Esther; Palmer, Steve; McNally, Alan; Muir, Peter; Vipond, Ian B.; Boyes, John; Sivaprakasam, Venkat; Salluja, Tranprit; Dervisevic, Samir; Meader, Emma J.; Park, Naomi R.; da Silva Filipe, Ana; Oliver, Karen; Jeffries, Aaron R.; Ott, Sascha; Williams, Chris A.; Simpson, David A.; Masoli, Jane A. 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I.; Burton-Fanning, Shirelle; Raviprakash, Veena; Sheriff, Nicola; Blakey, Victoria; Moore, Jonathan; Stonehouse, Susanne; Smith, Louise; Davidson, Rose K.; Bedford, Luke; Coupland, Lindsay; Chappell, Joseph G.; Tsoleridis, Theocharis; Ball, Jonathan; Willingham, Iona; Khakh, Manjinder; Fleming, Vicki M.; Williams, Rebecca J.; Lister, Michelle M.; Howson-Wells, Hannah C.; Wise, Emma; Berry, Louise; Boswell, Tim; Joseph, Amelia; Duckworth, Nichola; Walsh, Sarah; Moore, Nathan; Wyllie, Sarah; Mori, Matilde; Cortes, Nick; Kidd, Stephen; Gifford, Laura; Bicknell, Kelly; Spencer-Chapman, Michael H.; Lloyd, Allyson; Impey, Robert; Malone, Cassandra S.; Cogger, Benjamin J.; Levene, Nick; Monaghan, Lynn; Keeley, Alexander J.; Partridge, David G.; Raza, Mohammad; Evans, Cariad; Johnson, Kate; Betteridge, Emma; Farr, Ben W.; Goodwin, Scott; Scott, Carol; Shirley, Lesley; Thurston, Scott A. J.; Quail, Michael A.; Rajan, Diana; Bronner, Iraad F.; Williamson, Kathleen A.; Aigrain, Louise; Redshaw, Nicholas M.; McCarthy, Shane; Balcazar, Carlos E.; Gallagher, Michael D.; Lensing, Stefanie V.; Stanton, Thomas D.; Michelsen, Michelle L.; Makunin, Alex; Warwick-Dugdale, Joanna; Manley, Robin; Farbos, Audrey; Harrison, James W.; Sambles, Christine M.; Studholme, David J.; Lackenby, Angie; Mbisa, Tamyo; Platt, Steven; Miah, Shahjahan; Bibby, David; Manso, Carmen; Williams, David; Hubb, Jonathan; Dabrera, Gavin; Ramsay, Mary; Harrison, J. W.; Bradshaw, Daniel; Schaefer, Ulf; Groves, Natalie; Gallagher, Eileen; Lee, David; Ellaby, Nicholas; Hartman, Hassan; Patel, Vineet; Manesis, Nikos; Ledesma, Juan; Twohig, Katherine A.; Allara, Elias; Pearson, Clare; Cheng, Jeffrey K. J.; Bridgewater, Hannah E.; Frost, Lucy R.; Taylor-Joyce, Grace; Brown, Paul E.; Tong, Lily; Broos, Alice; Mair, Daniel; Nichols, Jenna; Whitehead, Mark; Carmichael, Stephen N.; Smollett, Katherine L.; Nomikou, Kyriaki; Wierzbicki, Claudia; Aranday-Cortes, Elihu; Johnson, Natasha; Webster, Hermione J.; Nickbakhsh, Seema; Vamos, Edith E.; Hughes, Margaret; Rainbow, Lucille; Eccles, Richard; Wilson, Harry D.; Nelson, Charlotte; Gregory, Richard; Gemmell, Matthew; Wilson, Rebekah E.; Fisher, Chloe L.; Signell, Adrian W.; Betancor, Gilberto; Nebbia, Gaia; Flaviani, Flavia; Cerda, Alberto C.; Merrill, Tammy V.; Cotic, Marius; Bayzid, Nadua; Thompson, Thomas; Acheson, Erwan; Zamudio, Marina Escalera; Rushton, Steven; Baker, David J.; O’Brien, Sarah; Rudder, Steven; Aydin, Alp; Sang, Fei; Debebe, Johnny; Francois, Sarah; Vasylyeva, Tetyana I.; Workman, Trudy; Gutierrez, Bernardo; Marchbank, Angela; Maksimovic, Joshua; Spellman, Karla; McCluggage, Kathryn; Morgan, Mari; Whiteley, Max; O'Brien, Sarah; Beer, Robert; Afifi, Safiah; Fuller, William; Whitwham, Andrew; Bresner, Catherine; Angyal, Adrienn; Green, Luke R.; Parsons, Paul J.; Tucker, Rachel M.; Brown, Rebecca; Bonfield, James; Puethe, Christoph; Rowe, Will; Liddle, Jennifier; Siveroni, Igor; Ariani, Cristina; Le-Viet, Thanh; Gaskin, Amy; Johnson, Rob; Abnizova, Irina; Ali, Mozam; Allen, Laura; Anderson, Ralph; Beale, Mathew; Austin-Guest, Siobhan; Bala, Sendu; Barrett, Jeffrey; Bassett, Andrew; Bellis, Katie L.; Battleday, Kristina; Beal, James; Bellany, Sam; Bellerby, Tristram; Berger, Duncan; Berriman, Matt; Bevan, Paul; Binley, Simon; Bishop, Jason; Blackburn, Kirsty; Boughton, Nick; Bowker, Sam; Brendler-Spaeth, Timothy; Bronner, Iraad; Brooklyn, Tanya; Buddenborg, Sarah Kay; Bush, Robert; Caetano, Catarina; Cagan, Alex; Carter, Nicola; Cartwright, Joanna; Monteiro, Tiago Carvalho; Chapman, Liz; Chillingworth, Tracey-Jane; Clapham, Peter; Clark, Richard; Clarke, Adrian; Clarke, Catriona; Cole, Daryl; Cook, Elizabeth; Coppola, Maria; 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Iqbal, Sameena; Jackson, Adam; Jackson, David; Verdejo, Carlos Jimenez; Jones, Matthew; Kallepally, Kalyan; Kay, Keely; Keatley, Jon; Keith, Alan; King, Alison; Kitchin, Lucy; Kleanthous, Matt; Klimekova, Martina; Korlevic, Petra; Krasheninnkova, Ksenia; Lane, Greg; Lensing, Stefanie; Langford, Cordelia; Laverack, Adam; Law, Katharine; Liddle, Jennifer; Lewis-Wade, Amanah; Lin, Quan; Lindsay, Sarah; Linsdell, Sally; Long, Rhona; Lovell, Jamie; Makunin, Aleksei; Lovell, Jon; Mack, James; Maddison, Mark; Mamun, Irfan; Mansfield, Jenny; Marriott, Neil; Martin, Matt; Mayho, Matthew; McClintock, Jo; McHugh, Sandra; MapcMinn, Liz; Meadows, Carl; Mobley, Emily; Moll, Robin; Morra, Maria; Morrow, Leanne; Murie, Kathryn; Nash, Sian; Nathwani, Claire; Naydenova, Plamena; Neaverson, Alexandra; Nerou, Ed; Nicholson, Jon; Nimz, Tabea; Noell, Guillaume G.; Ohan, Valeriu; O’Meara, Sarah; Olney, Charles; Ormond, Doug; Oszlanczi, Agnes; Pang, Yoke Fei; Pardubska, Barbora; Park, Naomi; Parmar, Aaron; Patel, Gaurang; Quail, Michael; Payne, Maggie; O'Meara, Sarah; Peacock, Sharon; Petersen, Arabella; Plowman, Deborah; Preston, Tom; Rance, Richard; Rawlings, Suzannah; Redshaw, Nicholas; Reynolds, Joe; Reynolds, Mark; Rice, Simon; Richardson, Matt; Roberts, Connor; Robinson, Katrina; Robinson, Melanie; Robinson, David; Rogers, Hazel; Rojo, Eduardo Martin; Roopra, Daljit; Rose, Mark; Rudd, Luke; Sadri, Ramin; Salmon, Nicholas; Saul, David; Schwach, Frank; Seekings, Phil; Simms, Alison; Sinnott, Matt; Sivadasan, Shanthi; Siwek, Bart; Sizer, Dale; Skeldon, Kenneth; Skelton, Jason; Slater-Tunstill, Joanna; Sloper, Lisa; Smerdon, Nathalie; Smith, Chris; Smith, Christen; Smith, James; Smith, Katie; Smith, Michelle; Smith, Sean; Smith, Tina; Sneade, Leighton; Soria, Carmen Diaz; Sousa, Catarina; Souster, Emily; Sparkes, Andrew; Spencer-Chapman, Michael; Squares, Janet; Stanley, Robert; Steed, Claire; Stickland, Tim; Wright, Sean; Taylor, Sam; Still, Ian; Stratton, Mike; Strickland, Michelle; Swann, Allen; Swiatkowska, Agnieszka; 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Cell Press, Cell Reports, 13(35), p. 109292, 2021

DOI: 10.1016/j.celrep.2021.109292

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Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B.1.1.7

Journal article published in 2021 by Bo Meng, Steven A. Kemp, Guido Papa, Rawlings Datir, Isabella A. T. M. Ferreira, Sara Marelli, William T. Harvey, Spyros Lytras, Ahmed Mohamed, Giulia Gallo, Covid-19 Genomics Uk (Cog-Uk) Consortium, Nazia Thakur

, Dami A. Collier, Petra Mlcochova, Justin O'Grady and other authors.

This paper is made freely available by the publisher.

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Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B.1.1.7