Published in
American Association for the Advancement of Science, Science Translational Medicine, 591(13), 2021
DOI: 10.1126/scitranslmed.abe7378
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SynNotch-CAR T cells overcome challenges of specificity, heterogeneity, and persistence in treating glioblastoma
Journal article published in 2021 by
Joseph H. Choe 
,
Payal B. Watchmaker ,
Milos S. Simic ,
Ryan D. Gilbert,
Aileen W. Li ,
Nira A. Krasnow,
Kira M. Downey ,
Wei Yu,
Diego A. Carrera,
Anna Celli ,
Juhyun Cho,
Jessica D. Briones ,
Jason M. Duecker,
Yitzhar E. Goretsky,
Ruth Dannenfelser
and other authors.
,
Payal B. Watchmaker ,
Milos S. Simic ,
Ryan D. Gilbert,
Aileen W. Li ,
Nira A. Krasnow,
Kira M. Downey ,
Wei Yu,
Diego A. Carrera,
Anna Celli ,
Juhyun Cho,
Jessica D. Briones ,
Jason M. Duecker,
Yitzhar E. Goretsky,
Ruth Dannenfelser
and other authors.
This paper was not found in any repository, but could be made available legally by the author.
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Abstract
SynNotch-CAR T cells durably clear glioblastoma xenografts, overcoming dual challenges of antigen heterogeneity and specificity common to solid tumors.