Changes in in-hospital mortality in the first wave of COVID-19: a multicentre prospective observational cohort study using the WHO Clinical Characterisation Protocol UK

Docherty, Annemarie B.; Harrison, Janet; Mulholland, Rachel H.; Lone, Nazir I.; Cheyne, Christopher P.; De Angelis, Daniela; Diaz-Ordaz, Karla; Drake, Thomas M.; Donegan, Cara; Dunning, Jake; Funk, Sebastian; Hardwick, Hayley E.; Girvan, Michelle; García-Fiñana, Marta; Ho, Antonia; Hughes, David M.; Keogh, Ruth H.; Kirwan, Peter D.; Leeming, Gary; Nguyen Van-Tam, Jonathan S.; Pius, Riinu; Russell, Clark D.; Tom, Brian Dm; Spencer, Rebecca G.; Turtle, Lance; Baillie, J. Kenneth; Openshaw, Peter Jm; Semple, Malcolm G.; Harrison, Ewen M.; Kenneth Baillie, J.; Carson, Gail; Alex, Beatrice; Bach, Benjamin; Barclay, Wendy S.; Bogaert, Debby; Chand, Meera; Cooke, Graham S.; Ab, Docherty; da Silva Filipe, Ana; Fletcher, Tom; Green, Christopher A.; Hiscox, Julian A.; Ho, Antonia Yw; Horby, Peter W.; Ijaz, Samreen; Khoo, Say; Klenerman, Paul; Law, Andrew; Lim, Wei Shen; Mentzer, Alexander J.; Merson, Laura; Meynert, Alison M.; Noursadeghi, Mahdad; Moore, Shona C.; Palmarini, Massimo; Paxton, William A.; Pollakis, Georgios; Rh, Mulholland; Price, Nicholas; Rambaut, Andrew; Robertson, David L.; Sancho-Shimizu, Vanessa; de Silva, Thushan; Scott, Janet T.; Sigfrid, Louise; Solomon, Tom; Sriskandan, Shiranee; Stuart, David; Summers, Charlotte; Tedder, Richard S.; Thompson, Aa Roger; Thomson, Emma C.; Turtle, Lance Cw; Thwaites, Ryan S.; Aa, Roger Thompson; Gupta, Rishi K.; Zambon, Maria; Palmieri, Carlo; Hardwick, Hayley; Donohue, Chloe; Lyons, Ruth; Griffiths, Fiona; Ni, Lone; Oosthuyzen, Wilna; Norman, Lisa; Fairfield, Cameron J.; Knight, Stephen R.; Mclean, Kenneth A.; Murphy, Derek; Shaw, Catherine A.; Dalton, Jo; Saviciute, Egle; Roberts, Stephanie; Marsh, Laura; Connor, Marie; Halpin, Sophie; Jackson, Clare; Gamble, Carrol; Wham, Murray; Clohisey, Sara; Hendry, Ross; Scott-Brown, James; Greenhalf, William; Shaw, Victoria; Cp, Cheyne; McDonald, Sarah E.; Keating, Seán; Ahmed, Katie A.; Armstrong, Jane A.; Ashworth, Milton; Asiimwe, Innocent G.; Bakshi, Siddharth; Barlow, Samantha L.; Booth, Laura; Brennan, Benjamin; Bullock, Katie; Catterall, Benjamin Wa; Clark, Jordan J.; Clarke, Emily A.; Cole, Sarah; Cooper, Louise; Cox, Helen; Davis, Christopher; Dincarslan, Oslem; Dunn, Chris; Dyer, Philip; Elliott, Angela; Evans, Anthony; Finch, Lorna; Fisher, Lewis Ws; Foster, Terry; Garcia-Dorival, Isabel; Gunning, Philip; Hartley, Catherine; Jensen, Rebecca L.; Jones, Christopher B.; Jones, Trevor R.; Khandaker, Shadia; King, Katharine; Kiy, Robyn T.; Koukorava, Chrysa; Lake, Annette; Lant, Suzannah; Latawiec, Diane; Lavelle-Langham, Lara; Lefteri, Daniella; Lett, Lauren; Livoti, Lucia A.; Mancini, Maria; McDonald, Sarah; McEvoy, Laurence; McLauchlan, John; Metelmann, Soeren; Miah, Nahida S.; Middleton, Joanna; Mitchell, Joyce; Matthew Ridley, P.; Murphy, Ellen G.; Penrice-Randal, Rebekah; Pilgrim, Jack; Prince, Tessa; Ridley, P. Matthew; Reynolds, Will; Sales, Debby; Shaw, Victoria E.; Shears, Rebecca K.; Small, Benjamin; Subramaniam, Krishanthi S.; Eunice Zhang, J.; Szemiel, Agnieska; Taggart, Aislynn; Tanianis-Hughes, Jolanta; Trochu, Erwan; Thomas, Jordan; van Tonder, Libby; Zhang, J. Eunice; Wilcock, Eve; Flaherty, Lisa; Maziere, Nicole; Doce Carracedo, Alejandra; Cass, Emily; Carlucci, Nicola; Holmes, Anthony; Massey, Hannah; Wrobel, Nicola; Murphy, Lee; Carracedo, Alejandra Doce; McCafferty, Sarah; Morrice, Kirstie; MacLean, Alan; Adeniji, Kayode; Agranoff, Daniel; Agwuh, Ken; Ail, Dhiraj; Aldera, Erin L.; Alegria, Ana; Angus, Brian; Ashish, Abdul; Atkinson, Dougal; Bari, Shahedal; Barlow, Gavin; Barnass, Stella; Barrett, Nicholas; Bassford, Christopher; Basude, Sneha; Baxter, David; Beadsworth, Michael; Bernatoniene, Jolanta; Berridge, John; Best, Nicola; Chadwick, David; Bothma, Pieter; Brittain-Long, Robin; Bulteel, Naomi; Burden, Tom; Burtenshaw, Andrew; Caruth, Vikki; Chambler, Duncan; Chee, Nigel; Child, Jenny; Chukkambotla, Srikanth; Clark, Tom; Collini, Paul; Cosgrove, Catherine; Cupitt, Jason; Cutino-Moguel, Maria-Teresa; Dark, Paul; Dawson, Chris; Dervisevic, Samir; Donnison, Phil; Douthwaite, Sam; DuRand, Ingrid; Dushianthan, Ahilanadan; Dyer, Tristan; Evans, Cariad; Eziefula, Chi; Fegan, Chrisopher; Finn, Adam; Tm, Drake; Garg, Sanjeev; Fullerton, Duncan; Garg, Atul; Gkrania-Klotsas, Effrossyni; Godden, Jo; Goldsmith, Arthur; Graham, Clive; Hardy, Elaine; Hartshorn, Stuart; Harvey, Daniel; Havalda, Peter; Hawcutt, Daniel B.; Hobrok, Maria; Hodgson, Luke; Hormis, Anil; Jacobs, Michael; Jain, Susan; Jennings, Paul; Kaliappan, Agilan; Kasipandian, Vidya; Kegg, Stephen; Kelsey, Michael; Kendall, Jason; Kerrison, Caroline; Kerslake, Ian; Koch, Oliver; Koduri, Gouri; Koshy, George; Laha, Shondipon; Laird, Steven; Larkin, Susan; Leiner, Tamas; Lillie, Patrick; Limb, James; Linnett, Vanessa; Little, Jeff; Lyttle, Mark; MacMahon, Michael; MacNaughton, Emily; Mankregod, Ravish; Masson, Huw; Matovu, Elijah; McCullough, Katherine; McEwen, Ruth; Meda, Manjula; Mills, Gary; Minton, Jane; Mirfenderesky, Mariyam; Mohandas, Kavya; Mok, Quen; Moon, James; Moore, Elinoor; Morgan, Patrick; Morris, Craig; Mortimore, Katherine; Moses, Samuel; Mpenge, Mbiye; Mulla, Rohinton; Murphy, Michael; Nagel, Megan; Nagarajan, Thapas; O'Shea, Matthew K.; Nelson, Mark; Otahal, Igor; Ostermann, Marlies; Pais, Mark; Panchatsharam, Selva; Papakonstantinou, Danai; Paraiso, Hassan; Patel, Brij; Pattison, Natalie; Pepperell, Justin; Peters, Mark; Phull, Mandeep; Singh Pooni, Jagtur; Pintus, Stefania; Post, Frank; Price, David; Prout, Rachel; Rae, Nikolas; Reschreiter, Henrik; Reynolds, Tim; Richardson, Neil; Roberts, Mark; Roberts, Devender; Rose, Alistair; Rousseau, Guy; Ryan, Brendan; Saluja, Taranprit; Shah, Aarti; Shanmuga, Prad; Sharma, Anil; Shawcross, Anna; Sizer, Jeremy; Shankar-Hari, Manu; Smith, Richard; Snelson, Catherine; Spittle, Nick; Staines, Nikki; Stambach, Tom; Stewart, Richard; Subudhi, Pradeep; Szakmany, Tamas; Tatham, Kate; Tridente, Ascanio; Thomas, Jo; Tupper-Carey, Darell; Thompson, Chris; Twagira, Mary; Thompson, Robert; Ustianowski, Andrew; Vallotton, Nick; Vincent-Smith, Lisa; Visuvanathan, Shico; Vuylsteke, Alan; Waddy, Sam; Wake, Rachel; Walden, Andrew; Welters, Ingeborg; Whitehouse, Tony; Whittaker, Paul; Whittington, Ashley; Wijesinghe, Meme; Papineni, Padmasayee; O′Shea, Matthew K.; Williams, Martin; Wilson, Lawrence; Winchester, Stephen; Sarah, Sarah; Wiselka, Martin; Pooni, Jagtur Singh; Wolverson, Adam; Wooton, Daniel G.; Workman, Andrew; Yates, Bryan; Young, Peter; Isaric4c, Investigators

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Daniela De Angelis
Docherty et al., 2021

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Elsevier, The Lancet Respiratory Medicine, 7(9), p. 773-785, 2021

DOI: 10.1016/s2213-2600(21)00175-2

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@article{Docherty2021,
  author = {Docherty, Annemarie B. and Harrison, Janet and Mulholland, Rachel H. and Lone, Nazir I. and Cheyne, Christopher P. and De Angelis, Daniela and Diaz-Ordaz, Karla and Drake, Thomas M. and Donegan, Cara and Dunning, Jake and Funk, Sebastian and Hardwick, Hayley E. and Girvan, Michelle and García-Fiñana, Marta and Ho, Antonia and Hughes, David M. and Keogh, Ruth H. and Kirwan, Peter D. and Leeming, Gary and Nguyen Van-Tam, Jonathan S. and Pius, Riinu and Russell, Clark D. and Tom, Brian Dm and Spencer, Rebecca G. and Turtle, Lance and Baillie, J. Kenneth and Openshaw, Peter Jm and Semple, Malcolm G. and Harrison, Ewen M. and Kenneth Baillie, J. and Carson, Gail and Alex, Beatrice and Bach, Benjamin and Barclay, Wendy S. and Bogaert, Debby and Chand, Meera and Cooke, Graham S. and Ab, Docherty and da Silva Filipe, Ana and Fletcher, Tom and Green, Christopher A. and Hiscox, Julian A. and Ho, Antonia Yw and Horby, Peter W. and Ijaz, Samreen and Khoo, Say and Klenerman, Paul and Law, Andrew and Lim, Wei Shen and Mentzer, Alexander J. and Merson, Laura and Meynert, Alison M. and Noursadeghi, Mahdad and Moore, Shona C. and Palmarini, Massimo and Paxton, William A. and Pollakis, Georgios and Rh, Mulholland and Price, Nicholas and Rambaut, Andrew and Robertson, David L. and Sancho-Shimizu, Vanessa and de Silva, Thushan and Scott, Janet T. and Sigfrid, Louise and Solomon, Tom and Sriskandan, Shiranee and Stuart, David and Summers, Charlotte and Tedder, Richard S. and Thompson, Aa Roger and Thomson, Emma C. and Turtle, Lance Cw and Thwaites, Ryan S. and Aa, Roger Thompson and Gupta, Rishi K. and Zambon, Maria and Palmieri, Carlo and Hardwick, Hayley and Donohue, Chloe and Lyons, Ruth and Griffiths, Fiona and Ni, Lone and Oosthuyzen, Wilna and Norman, Lisa and Fairfield, Cameron J. and Knight, Stephen R. and Mclean, Kenneth A. and Murphy, Derek and Shaw, Catherine A. and Dalton, Jo and Saviciute, Egle and Roberts, Stephanie and Marsh, Laura and Connor, Marie and Halpin, Sophie and Jackson, Clare and Gamble, Carrol and Wham, Murray and Clohisey, Sara and Hendry, Ross and Scott-Brown, James and Greenhalf, William and Shaw, Victoria and Cp, Cheyne and McDonald, Sarah E. and Keating, Seán and Ahmed, Katie A. and Armstrong, Jane A. and Ashworth, Milton and Asiimwe, Innocent G. and Bakshi, Siddharth and Barlow, Samantha L. and Booth, Laura and Brennan, Benjamin and Bullock, Katie and Catterall, Benjamin Wa and Clark, Jordan J. and Clarke, Emily A. and Cole, Sarah and Cooper, Louise and Cox, Helen and Davis, Christopher and Dincarslan, Oslem and Dunn, Chris and Dyer, Philip and Elliott, Angela and Evans, Anthony and Finch, Lorna and Fisher, Lewis Ws and Foster, Terry and Garcia-Dorival, Isabel and Gunning, Philip and Hartley, Catherine and Jensen, Rebecca L. and Jones, Christopher B. and Jones, Trevor R. and Khandaker, Shadia and King, Katharine and Kiy, Robyn T. and Koukorava, Chrysa and Lake, Annette and Lant, Suzannah and Latawiec, Diane and Lavelle-Langham, Lara and Lefteri, Daniella and Lett, Lauren and Livoti, Lucia A. and Mancini, Maria and McDonald, Sarah and McEvoy, Laurence and McLauchlan, John and Metelmann, Soeren and Miah, Nahida S. and Middleton, Joanna and Mitchell, Joyce and Matthew Ridley, P. and Murphy, Ellen G. and Penrice-Randal, Rebekah and Pilgrim, Jack and Prince, Tessa and Ridley, P. Matthew and Reynolds, Will and Sales, Debby and Shaw, Victoria E. and Shears, Rebecca K. and Small, Benjamin and Subramaniam, Krishanthi S. and Eunice Zhang, J. and Szemiel, Agnieska and Taggart, Aislynn and Tanianis-Hughes, Jolanta and Trochu, Erwan and Thomas, Jordan and van Tonder, Libby and Zhang, J. Eunice and Wilcock, Eve and Flaherty, Lisa and Maziere, Nicole and Doce Carracedo, Alejandra and Cass, Emily and Carlucci, Nicola and Holmes, Anthony and Massey, Hannah and Wrobel, Nicola and Murphy, Lee and Carracedo, Alejandra Doce and McCafferty, Sarah and Morrice, Kirstie and MacLean, Alan and Adeniji, Kayode and Agranoff, Daniel and Agwuh, Ken and Ail, Dhiraj and Aldera, Erin L. and Alegria, Ana and Angus, Brian and Ashish, Abdul and Atkinson, Dougal and Bari, Shahedal and Barlow, Gavin and Barnass, Stella and Barrett, Nicholas and Bassford, Christopher and Basude, Sneha and Baxter, David and Beadsworth, Michael and Bernatoniene, Jolanta and Berridge, John and Best, Nicola and Chadwick, David and Bothma, Pieter and Brittain-Long, Robin and Bulteel, Naomi and Burden, Tom and Burtenshaw, Andrew and Caruth, Vikki and Chambler, Duncan and Chee, Nigel and Child, Jenny and Chukkambotla, Srikanth and Clark, Tom and Collini, Paul and Cosgrove, Catherine and Cupitt, Jason and Cutino-Moguel, Maria-Teresa and Dark, Paul and Dawson, Chris and Dervisevic, Samir and Donnison, Phil and Douthwaite, Sam and DuRand, Ingrid and Dushianthan, Ahilanadan and Dyer, Tristan and Evans, Cariad and Eziefula, Chi and Fegan, Chrisopher and Finn, Adam and Tm, Drake and Garg, Sanjeev and Fullerton, Duncan and Garg, Atul and Gkrania-Klotsas, Effrossyni and Godden, Jo and Goldsmith, Arthur and Graham, Clive and Hardy, Elaine and Hartshorn, Stuart and Harvey, Daniel and Havalda, Peter and Hawcutt, Daniel B. and Hobrok, Maria and Hodgson, Luke and Hormis, Anil and Jacobs, Michael and Jain, Susan and Jennings, Paul and Kaliappan, Agilan and Kasipandian, Vidya and Kegg, Stephen and Kelsey, Michael and Kendall, Jason and Kerrison, Caroline and Kerslake, Ian and Koch, Oliver and Koduri, Gouri and Koshy, George and Laha, Shondipon and Laird, Steven and Larkin, Susan and Leiner, Tamas and Lillie, Patrick and Limb, James and Linnett, Vanessa and Little, Jeff and Lyttle, Mark and MacMahon, Michael and MacNaughton, Emily and Mankregod, Ravish and Masson, Huw and Matovu, Elijah and McCullough, Katherine and McEwen, Ruth and Meda, Manjula and Mills, Gary and Minton, Jane and Mirfenderesky, Mariyam and Mohandas, Kavya and Mok, Quen and Moon, James and Moore, Elinoor and Morgan, Patrick and Morris, Craig and Mortimore, Katherine and Moses, Samuel and Mpenge, Mbiye and Mulla, Rohinton and Murphy, Michael and Nagel, Megan and Nagarajan, Thapas and O'Shea, Matthew K. and Nelson, Mark and Otahal, Igor and Ostermann, Marlies and Pais, Mark and Panchatsharam, Selva and Papakonstantinou, Danai and Paraiso, Hassan and Patel, Brij and Pattison, Natalie and Pepperell, Justin and Peters, Mark and Phull, Mandeep and Singh Pooni, Jagtur and Pintus, Stefania and Post, Frank and Price, David and Prout, Rachel and Rae, Nikolas and Reschreiter, Henrik and Reynolds, Tim and Richardson, Neil and Roberts, Mark and Roberts, Devender and Rose, Alistair and Rousseau, Guy and Ryan, Brendan and Saluja, Taranprit and Shah, Aarti and Shanmuga, Prad and Sharma, Anil and Shawcross, Anna and Sizer, Jeremy and Shankar-Hari, Manu and Smith, Richard and Snelson, Catherine and Spittle, Nick and Staines, Nikki and Stambach, Tom and Stewart, Richard and Subudhi, Pradeep and Szakmany, Tamas and Tatham, Kate and Tridente, Ascanio and Thomas, Jo and Tupper-Carey, Darell and Thompson, Chris and Twagira, Mary and Thompson, Robert and Ustianowski, Andrew and Vallotton, Nick and Vincent-Smith, Lisa and Visuvanathan, Shico and Vuylsteke, Alan and Waddy, Sam and Wake, Rachel and Walden, Andrew and Welters, Ingeborg and Whitehouse, Tony and Whittaker, Paul and Whittington, Ashley and Wijesinghe, Meme and Papineni, Padmasayee and O′Shea, Matthew K. and Williams, Martin and Wilson, Lawrence and Winchester, Stephen and Sarah, Sarah and Wiselka, Martin and Pooni, Jagtur Singh and Wolverson, Adam and Wooton, Daniel G. and Workman, Andrew and Yates, Bryan and Young, Peter and Isaric4c, Investigators},
  doi = {10.1016/s2213-2600(21)00175-2},
  journal = {The Lancet Respiratory Medicine},
  month = {may},
  pages = {773-785},
  title = {Changes in in-hospital mortality in the first wave of COVID-19: a multicentre prospective observational cohort study using the WHO Clinical Characterisation Protocol UK},
  url = {https://oadoi.org/10.1016/s2213-2600(21)00175-2},
  volume = {9},
  year = {2021}
}

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