Published in
American Association for the Advancement of Science, Science Advances, 19(7), 2021
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NOX4 links metabolic regulation in pancreatic cancer to endoplasmic reticulum redox vulnerability and dependence on PRDX4
Journal article published in 2021 by
Pallavi Jain,
Anna Dvorkin-Gheva 
,
Erik Mollen,
Lucie Malbeteau,
Michael Xie,
Fatima Jessa,
Piriththiv Dhavarasa,
Kevin R. Brown,
Stephen Chung,
Gun Ho Jang,
Brown Kr,
Jang Gh,
Parth Vora,
Faiyaz Notta,
Jason Moffat
and other authors.
,
Erik Mollen,
Lucie Malbeteau,
Michael Xie,
Fatima Jessa,
Piriththiv Dhavarasa,
Kevin R. Brown,
Stephen Chung,
Gun Ho Jang,
Brown Kr,
Jang Gh,
Parth Vora,
Faiyaz Notta,
Jason Moffat
and other authors.
This paper is made freely available by the publisher.
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Abstract
Reductive power in the cytosol of pancreatic cancer cells drives a dependency on the endoplasmic reticulum protein PRDX4.