Published in
Royal Society of Chemistry, Chemical Science, 15(12), p. 5438-5449, 2021
DOI: 10.1039/d0sc06083f
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Targeted 1,3-dipolar cycloaddition with acrolein for cancer prodrug activation
Journal article published in 2021 by
Ambara R. Pradipta 
,
Peni Ahmadi ,
Kazuki Terashima,
Kyohei Muguruma ,
Motoko Fujii,
Tomoya Ichino,
Satoshi Maeda ,
Katsunori Tanaka
,
Peni Ahmadi ,
Kazuki Terashima,
Kyohei Muguruma ,
Motoko Fujii,
Tomoya Ichino,
Satoshi Maeda ,
Katsunori Tanaka
This paper is made freely available by the publisher.
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Abstract
Prodrug activation strategy by utilizing the reaction between aryl azide and endogenous acrolein that is generally overproduced by cancer cells.