Dissemin is shutting down on January 1st, 2025

Published in

American Association for the Advancement of Science, Science Advances, 8(7), 2021

DOI: 10.1126/sciadv.abe5496

Links

Tools

Export citation

Search in Google Scholar

Quantification of Cas9 binding and cleavage across diverse guide sequences maps landscapes of target engagement

Journal article published in 2021 by Evan A. Boyle ORCID, Winston R. Becker ORCID, Hua B. Bai ORCID, Janice S. Chen ORCID, Jennifer A. Doudna ORCID, William J. Greenleaf ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

Full text: Download

Green circle
Preprint: archiving allowed
Upload
Red circle
Postprint: archiving forbidden
Green circle
Published version: archiving allowed
Upload
Policy details
Data provided by SHERPA/RoMEO

Abstract

A massive new resource of diverse Cas9 binding and cleavage events establishes new rules for effective CRISPR targeting.