Published in

Oxford University Press, Bioscience, Biotechnology, and Biochemistry, 3(85), p. 687-690, 2021

DOI: 10.1093/bbb/zbaa055

Links

Tools

Export citation

Search in Google Scholar

Production of a new triterpenoid disaccharide saponin from sequential glycosylation of ganoderic acid A by 2 Bacillus glycosyltransferases

Journal article published in 2021 by Te-Sheng Chang, Chien-Min Chiang, Jiumn-Yih Wu, Yu-Li Tsai, Huei-Ju Ting ORCID
Distributing this paper is prohibited by the publisher
Distributing this paper is prohibited by the publisher

Full text: Unavailable

Green circle
Preprint: archiving allowed
Upload
Orange circle
Postprint: archiving restricted
Upload
Red circle
Published version: archiving forbidden
Policy details
Data provided by SHERPA/RoMEO

Abstract

ABSTRACT Ganoderic acid A (GAA) is a lanostane-type triterpenoid, isolated from medicinal fungus Ganoderma lucidum, and possesses multiple bioactivities. In the present study, GAA was sequentially biotransformed by 2 recently discovered Bacillus glycosyltransferases (GT), BtGT_16345 and BsGT110, and the final product was purified and identified as a new compound, GAA-15,26-O-β-diglucoside, which showed 1024-fold aqueous solubility than GAA.