The osteoarchaeological collection from the roman period at Quart street of Valencia comprises 181 inhumations from the Republican to the Roman Empire period (2nd BC to III AD). This is the oldest cemetery excavated in the city where a very significant sample of the foundational population from the 138 BC was found. In this work, the results from the funerary analysis, the bio-anthropological, palepathological and the paleodiet are discussed. The individuals came from a group of burials found at some hypogea belonging to the oldest part of the necropolis which coincided with the foundation of the city on the last third of the 2nd century BC