6 million sexually active women are at risk of developing cervical cancer in Cameroon. About 2000 cases are reported annually with 55% of them being fatal. The fight against this disease is hampered by both poor material and human resources. Methods of prevention are divided into primary, secondary, and tertiary. Vaccination is one of the primary methods of prevention of cervical cancer. Despite the avoidable nature of this disease, there is a growing hesitancy in society to allow girls to be vaccinated. The objective of this study is to find out the characteristics of parents who allow their daughter(s ) to be vaccinated, despite the negative growing opinion about vaccination. Sensitization on the importance of prevention of cervical cancer by the public authorities, financial empowerment of women, and level of education seem crucial to increase the uptake of vaccination against the Human Papilloma Virus.