Published in
American Association for the Advancement of Science, Science Translational Medicine, 579(13), 2021
DOI: 10.1126/scitranslmed.abb2181
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NITD-688, a pan-serotype inhibitor of the dengue virus NS4B protein, shows favorable pharmacokinetics and efficacy in preclinical animal models
Journal article published in 2021 by
Stephanie A. Moquin 
,
Oliver Simon,
Ratna Karuna ,
Suresh B. Lakshminarayana ,
Fumiaki Yokokawa ,
Feng Wang ,
Chandra Saravanan,
Jin Zhang,
Craig W. Day,
Katherine Chan ,
Qing-Yin Wang,
Siyan Lu ,
Hongping Dong ,
Kah Fei Wan,
Siew Pheng Lim
and other authors.
,
Oliver Simon,
Ratna Karuna ,
Suresh B. Lakshminarayana ,
Fumiaki Yokokawa ,
Feng Wang ,
Chandra Saravanan,
Jin Zhang,
Craig W. Day,
Katherine Chan ,
Qing-Yin Wang,
Siyan Lu ,
Hongping Dong ,
Kah Fei Wan,
Siew Pheng Lim
and other authors.
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Abstract
NITD-688, a pan-serotype dengue virus inhibitor, is effective in mice and is well tolerated with favorable pharmacokinetics in animal models.