Published in

American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 4(65), 2021

DOI: 10.1128/aac.02004-20

Links

Tools

Export citation

Search in Google Scholar

Synergistic Quinolone Sensitization by Targeting the recA SOS Response Gene and Oxidative Stress

Journal article published in 2021 by S. Diaz-Diaz ORCID, E. Recacha ORCID, J. Machuca ORCID, A. García-Duque, F. Docobo-Pérez ORCID, J. Blázquez ORCID, A. Pascual ORCID, J. M. Rodríguez-Martínez ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

Full text: Unavailable

Green circle
Preprint: archiving allowed
Upload
Green circle
Postprint: archiving allowed
Upload
Orange circle
Published version: archiving restricted
Upload
Policy details
Data provided by SHERPA/RoMEO

Abstract

Suppression of the recA SOS response gene and reactive oxygen species (ROS) overproduction have been shown, separately, to enhance fluoroquinolone activity and lethality. Their putative synergistic impact as a strategy to potentiate the efficacy of bactericidal antimicrobial agents such as fluoroquinolones is unknown.