Exploring the Impact of Ketodeoxynonulosonic Acid in Host-Pathogen Interactions Using Uptake and Surface Display by Nontypeable Haemophilus influenzae
Journal article published in 2021 by
Sudeshna Saha 
,
Alison Coady ,
Aniruddha Sasmal,
Kunio Kawanishi ,
Biswa Choudhury,
Hai Yu ,
Ricardo U. Sorensen,
Jaime Inostroza,
Ian C. Schoenhofen,
Xi Chen ,
Anja Münster-Kühnel,
Chihiro Sato,
Ken Kitajima,
Sanjay Ram,
Victor Nizet
and other authors.
,
Alison Coady ,
Aniruddha Sasmal,
Kunio Kawanishi ,
Biswa Choudhury,
Hai Yu ,
Ricardo U. Sorensen,
Jaime Inostroza,
Ian C. Schoenhofen,
Xi Chen ,
Anja Münster-Kühnel,
Chihiro Sato,
Ken Kitajima,
Sanjay Ram,
Victor Nizet
and other authors.
This paper is made freely available by the publisher.
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Abstract
All cells in vertebrates are coated with a dense array of glycans often capped with sugars called sialic acids. Sialic acids have many functions, including serving as a signal for recognition of “self” cells by the immune system, thereby guiding an appropriate immune response against foreign “nonself” and/or damaged cells.