Domestic gas-steam combined cycle units start and stop frequently, and the load changes greatly, which accelerate the expansion of defects, such as fatigue, cracks, and organizational deterioration of metal components. In view of the problems caused by the material selection characteristics of gas-steam combined cycle units and the daily shutdown mode, several common typical cases of gas-steam combined cycle units are analyzed, such as compressor blade fatigue fracture, main steam combined valve body fatigue cracks, pipeline and pressure vessel weld fatigue cracks. As well, the gas-steam combined cycle unit metal supervision content and inspection emphasis are studied and supplemented.