Published in
American Association for the Advancement of Science, Science Translational Medicine, 575(13), 2021
DOI: 10.1126/scitranslmed.abd2655
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A genome-wide CRISPR-based screen identifies KAT7 as a driver of cellular senescence
Journal article published in 2021 by
Wei Wang 
,
Yuxuan Zheng ,
Shuhui Sun ,
Wei Li ,
Moshi Song,
Qianzhao Ji,
Zeming Wu,
Zunpeng Liu,
Yanling Fan,
Feifei Liu,
Jingyi Li,
Concepcion Rodriguez Esteban,
Si Wang ,
Qi Zhou ,
Juan Carlos Izpisua Belmonte
and other authors.
,
Yuxuan Zheng ,
Shuhui Sun ,
Wei Li ,
Moshi Song,
Qianzhao Ji,
Zeming Wu,
Zunpeng Liu,
Yanling Fan,
Feifei Liu,
Jingyi Li,
Concepcion Rodriguez Esteban,
Si Wang ,
Qi Zhou ,
Juan Carlos Izpisua Belmonte
and other authors.
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Abstract
Inactivation of the histone acetyltransferase gene KAT7 prolongs survival in naturally aged mice and progeroid mice that age prematurely.