Urinary Leukotriene E4and Prostaglandin D2Metabolites Increase in Adult and Childhood Severe Asthma Characterized by Type 2 Inflammation. A Clinical Observational Study

Kolmert, Johan; Gómez, Cristina; Balgoma, David; Sjödin, Marcus; Bood, Johan; Konradsen, Jon R.; Ericsson, Magnus; Thörngren, John-Olof; James, Anna; Mikus, Maria; Sousa, Ana R.; Riley, John H.; Bates, Stewart; Bakke, Per S.; Pandis, Ioannis; Caruso, Massimo; Chanez, Pascal; Fowler, Stephen J.; Geiser, Thomas; Howarth, Peter; Horváth, Ildikó; Krug, Norbert; Montuschi, Paolo; Sanak, Marek; Behndig, Annelie; Shaw, Dominick E.; Knowles, Richard G.; Holweg, Cécile T. J.; Wheelock, Åsa M.; Dahlén, Barbro; Nordlund, Björn; Alving, Kjell; Hedlin, Gunilla; Chung, Kian Fan; Adcock, Ian M.; Sterk, Peter J.; Djukanovic, Ratko; Dahlén, Sven-Erik; Wheelock, Craig E.; Ahmed, H.; Auffray, C.; Bansal, A. T.; Bel, E. H.; Bigler, J.; Billing, B.; Baribaud, F.; Bisgaard, H.; Boedigheimer, M. J.; Bønnelykke, K.; Brandsma, J.; Brinkman, P.; Bucchioni, E.; Burg, D.; Bush, A.; Chaiboonchoe, A.; Compton, C. H.; Corfield, J.; Cunoosamy, D.; D’Amico, A.; De Meulder, B.; Erpenbeck, V. J.; Erzen, D.; Fichtner, K.; Fitch, N.; Fleming, L. J.; Formaggio, E.; Frey, U.; Gahlemann, M.; Goss, V.; Guo, Y.; Hashimoto, S.; Haughney, J.; Hekking, P. W.; Higenbottam, T.; Hohlfeld, J. M.; Knox, A. J.; Lazarinis, N.; Lefaudeux, D.; Loza, M. J.; Lutter, R.; Manta, A.; Masefield, S.; Matthews, J. G.; Mazein, A.; Meiser, A.; Middelveld, R. J. M.; Miralpeix, M.; Mores, N.; Murray, C. S.; Musial, J.; Myles, D.; Pahus, L.; Pavlidis, S.; Postle, A.; Powel, P.; Praticò, G.; PuigValls, M.; Rao, N.; Roberts, A.; Roberts, G.; Rowe, A.; Sandström, T.; Schofield, J. P. R.; Seibold, W.; Selby, A.; Sigmund, R.; Singer, F.; Skipp, P. J.; Smicker, M.; Sun, K.; Thornton, B.; Uddin, M.; van Aalderen, W. M.; van Geest, M.; Vestbo, J.; Vissing, N. H.; Wagener, A. H.; Wagers, S. S.; Weiszhart, Z.; Wilson, S. J.; Östling, J.; Ahmed, H.; Auffray, C.; Bansal, A. T.; Bel, E. H.; Bigler, J.; Billing, B.; Baribaud, F.; Bisgaard, H.; Boedigheimer, M. J.; Bønnelykke, K.; Brandsma, J.; Brinkman, P.; Bucchioni, E.; Burg, D.; Bush, A.; Chaiboonchoe, A.; Compton, C. H.; Corfield, J.; Cunoosamy, D.; D’Amico, A.; De Meulder, B.; Erpenbeck, V. J.; Erzen, D.; Fichtner, K.; Fitch, N.; Fleming, L. J.; Formaggio, E.; Frey, U.; Gahlemann, M.; Goss, V.; Guo, Y.; Hashimoto, S.; Haughney, J.; Hekking, P. W.; Higenbottam, T.; Hohlfeld, J. M.; Knox, A. J.; Lazarinis, N.; Lefaudeux, D.; Loza, M. J.; Lutter, R.; Manta, A.; Masefield, S.; Matthews, J. G.; Mazein, A.; Meiser, A.; Middelveld, R. J. M.; Miralpeix, M.; Mores, N.; Murray, C. S.; Musial, J.; Myles, D.; Pahus, L.; Pavlidis, S.; Postle, A.; Powel, P.; Praticò, G.; PuigValls, M.; Rao, N.; Roberts, A.; Roberts, G.; Rowe, A.; Sandström, T.; Schofield, J. P. R.; Seibold, W.; Selby, A.; Sigmund, R.; Singer, F.; Skipp, P. J.; Smicker, M.; Sun, K.; Thornton, B.; Uddin, M.; van Aalderen, W. M.; van Geest, M.; Vestbo, J.; Vissing, N. H.; Wagener, A. H.; Wagers, S. S.; Weiszhart, Z.; Wilson, S. J.; Östling, J.

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American Thoracic Society, American Journal of Respiratory and Critical Care Medicine, 1(203), p. 37-53, 2021

DOI: 10.1164/rccm.201909-1869oc

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Urinary Leukotriene E4and Prostaglandin D2Metabolites Increase in Adult and Childhood Severe Asthma Characterized by Type 2 Inflammation. A Clinical Observational Study

Journal article published in 2021 by Johan Kolmert

, Cristina Gómez, David Balgoma, Marcus Sjödin, Johan Bood, Jon R. Konradsen, Magnus Ericsson, John-Olof Thörngren, Anna James, Maria Mikus

, Ana R. Sousa, John H. Riley, Stewart Bates, Per S. Bakke, Ioannis Pandis and other authors.

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Urinary Leukotriene E<sub>4</sub>and Prostaglandin D<sub>2</sub>Metabolites Increase in Adult and Childhood Severe Asthma Characterized by Type 2 Inflammation. A Clinical Observational Study