Published in
American Society for Microbiology, Journal of Virology, 6(95), 2021
DOI: 10.1128/jvi.02148-20
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Relative DNA methylation and demethylation efficiencies during postnatal liver development regulate hepatitis B virus biosynthesis
Journal article published in 2020 by
Claudia E. Oropeza,
Grant Tarnow,
Taha Y. Taha 
,
Rasha E. Shalaby,
Marieta V. Hyde,
Mark Maienschein-Cline,
Stefan J. Green ,
Alan McLachlan
,
Rasha E. Shalaby,
Marieta V. Hyde,
Mark Maienschein-Cline,
Stefan J. Green ,
Alan McLachlan
This paper was not found in any repository, but could be made available legally by the author.
Full text: Unavailable
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Abstract
HBV biosynthesis begins at birth and increases during early postnatal liver development in the HBV transgenic mouse model of chronic infection. The levels of viral RNA and DNA synthesis correlate with pioneer transcription factor FoxA transcript plus Tet methylcytosine dioxygenase-generated 5hmC abundance but inversely with Dnmt transcript levels and HBV DNA methylation.