BACKGROUND: Tuberculosis (TB) remains a global health problem, and in Indonesia, although TB control efforts have been carried out since 1995. TB is ranked 9th as the leading cause of death worldwide. The increase in the number of TB cases caused by risk factors triggering include a decrease in the immune system caused by HIV infection, nutritional status, education, sex, occupation, air humidity, house ventilation, temperature, occupancy density lighting, and contact history. AIM: This study aimed to analyze the relationship of nutritional status, contact history, and smoking to the incidence of pulmonary TB in Community Health Centre Tamalatea of Jeneponto District. METOHDS: This type of research is analytic observational with a case–control design with a total sample of 147 samples consisting of 49 cases and 98 controls. Data collection was conducted from August to October 2019. Data analysis used in the study was univariate and bivariate analysis with Chi-square test. RESULTS: The results showed that nutritional status (OR=5.403 95% CI: 2.547–11.461), contact history (OR=13.971 95% CI: 3.807–51.262), and smoking (OR=2.782 95% CI: 1.370–5.648) are related to the incidence of pulmonary in Community Health Centre Tamalatea of Jeneponto District. TB officers are expected to intensify the home visit program, especially for pulmonary TB sufferers with a considerable distance from the community health center, with transportation constraints and relatively poor economic conditions so that the health status of pulmonary TB sufferers can be monitored properly. CONCLUSION: TB officers are expected to intensify the home visit program, especially for pulmonary TB sufferers with a considerable distance from the Puskesmas, with transportation constraints and relatively poor economic conditions so that the health status of pulmonary TB sufferers can be monitored properly.