American Society for Microbiology, Applied and Environmental Microbiology, 5(87), 2021
DOI: 10.1128/aem.02597-20
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Colistin (polymyxin E) is an antimicrobial with poor solubility in agar-based media, and therefore, broth microdilution is the only available method for determining phenotypic resistance. However, estimating colistin resistance in mixed Escherichia coli populations is laborious, since it requires individual colony isolation, identification, and susceptibility testing.