Published in
American Association for the Advancement of Science, Science Translational Medicine, 574(12), 2020
DOI: 10.1126/scitranslmed.abb9283
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Receptor-gated IL-2 delivery by an anti-human IL-2 antibody activates regulatory T cells in three different species
Journal article published in 2020 by
Ufuk Karakus 
,
Dilara Sahin ,
Peer R. E. Mittl,
Petra Mooij ,
Gerrit Koopman,
Onur Boyman
,
Dilara Sahin ,
Peer R. E. Mittl,
Petra Mooij ,
Gerrit Koopman,
Onur Boyman
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Abstract
CD25-biased human IL-2 complexes stimulate regulatory T cells in freshly isolated human T cells ex vivo and in mice and rhesus macaques in vivo.