Published in

American Society for Microbiology, Journal of Clinical Microbiology, 3(59), 2021

DOI: 10.1128/jcm.02314-20

Links

Tools

Export citation

Search in Google Scholar

Xpert MTB/XDR: a 10-Color Reflex Assay Suitable for Point-of-Care Settings To Detect Isoniazid, Fluoroquinolone, and Second-Line-Injectable-Drug Resistance Directly from Mycobacterium tuberculosis-Positive Sputum

Journal article published in 2021 by Yuan Cao, Heta Parmar, Rajiv L. Gaur, Deanna Lieu, Shobana Raghunath, Nova Via, Simone Battaglia, Daniela M. Cirillo ORCID, Claudia Denkinger, Sophia Georghiou ORCID, Robert Kwiatkowski, David Persing, David Alland ORCID, Soumitesh Chakravorty
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

Full text: Download

Green circle
Preprint: archiving allowed
Upload
Green circle
Postprint: archiving allowed
Upload
Orange circle
Published version: archiving restricted
Upload
Policy details
Data provided by SHERPA/RoMEO

Abstract

We describe the design, development, analytical performance, and a limited clinical evaluation of the 10-color Xpert MTB/XDR assay (CE-IVD only, not for sale in the United States). This assay is intended as a reflex test to detect resistance to isoniazid (INH), fluoroquinolones (FLQ), ethionamide (ETH), and second-line injectable drugs (SLIDs) in unprocessed sputum samples and concentrated sputum sediments which are positive for Mycobacterium tuberculosis .