Published in
Royal Society of Chemistry, Chemical Science, 5(12), p. 1869-1885, 2021
DOI: 10.1039/d0sc05971d
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The structure of human dermatan sulfate epimerase 1 emphasizes the importance of C5-epimerization of glucuronic acid in higher organisms
Journal article published in 2021 by
Mahmudul Hasan 
,
Hamed Khakzad ,
Lotta Happonen ,
Anders Sundin ,
Johan Unge ,
Uwe Mueller ,
Johan Malmström ,
Gunilla Westergren-Thorsson ,
Lars Malmström ,
Ulf Ellervik ,
Anders Malmström ,
Emil Tykesson
,
Hamed Khakzad ,
Lotta Happonen ,
Anders Sundin ,
Johan Unge ,
Uwe Mueller ,
Johan Malmström ,
Gunilla Westergren-Thorsson ,
Lars Malmström ,
Ulf Ellervik ,
Anders Malmström ,
Emil Tykesson
This paper is made freely available by the publisher.
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Abstract
Structural studies of human DS-epi1 suggests a new catalytic isomerization mechanism and reveals remarkable similarities to bacterial proteins.