ABSTRACT The introduction of new crops in northeastern Brazil, associated with the use of the green manure, can become an alternative for family farmers. Thus, the objective of this work was to determine the effect of green manuring with M. aegyptia L. on the agro-economic efficiency of radish production. The experimental design was a randomised complete block with four treatments and five replicates; the treatments were composed of four doses of M. aegyptia (20, 35, 50 and 65 t ha-1 on a dry basis) incorporated into the soil in three cropping periods. In radish plants, we evaluated plant height, fresh and dry mass of shoots, total and commercial productivity of roots, productivity of scrap roots, dry mass of roots and root diameter. The economic indicators gross income, net income, rate of return and profit margin were used to evaluate the agro-economic efficiency of the system. The maximum agronomic efficiency was reached with a commercial root productivity of 7.86 t ha-1 and the addition of 49.29 t ha-1 of green manure. The maximum economic efficiency was obtained with a net income of 11,955.46 R$ ha-1 when a green manure dose of 46.00 t ha-1 was added. The use of M. aegyptia as green manure is economically viable in the production of radish in the semi-arid region of Northeast Brazil.