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Oxford University Press, Journal of the Pediatric Infectious Diseases Society, 5(10), p. 669-673, 2020

DOI: 10.1093/jpids/piaa161

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Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) Antibody Responses in Children With Multisystem Inflammatory Syndrome in Children (MIS-C) and Mild and Severe Coronavirus Disease 2019 (COVID-19)

Journal article published in 2020 by Elizabeth M. Anderson, Caroline Diorio, Eileen C. Goodwin, Kevin O. McNerney ORCID, Madison E. Weirick, Sigrid Gouma, Marcus J. Bolton, Claudia P. Arevalo, Julie Chase, Philip Hicks, Tomaz B. Manzoni ORCID, Amy E. Baxter, Kurt P. Andrea, Chakkapong Burudpakdee, Jessica H. Lee and other authors.
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Abstract Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) antibody responses in children remain poorly characterized. Here, we show that pediatric patients with multisystem inflammatory syndrome in children (MIS-C) possess higher SARS-CoV-2 spike immunoglobulin G (IgG) titers compared with those with severe coronavirus disease 2019, likely reflecting a longer time since the onset of infection in MIS-C patients.