Stable π-radical nanoparticles as versatile photosensitizers for effective hypoxia-overcoming photodynamic therapy
Journal article published in 2021 by
Xiao Cui,
Guihong Lu,
Shengzhi Dong,
Shengliang Li 
,
Yafang Xiao ,
Jinfeng Zhang ,
Yanhong Liu,
Xiangmin Meng ,
Feng Li ,
Chun-Sing Lee
,
Yafang Xiao ,
Jinfeng Zhang ,
Yanhong Liu,
Xiangmin Meng ,
Feng Li ,
Chun-Sing Lee
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Abstract
A stable π-radical is used as a photosensitizer for photodynamic therapy. Under hypoxic conditions, sufficient O2−˙ generation and cytotoxicity were observed addressing the most important hurdle for successful PDT in a tumor microenvironment.