Urban green infrastructure (UGI) has the potential to address a wide range of challenges associated with rapidly growing cities in a changing climate, while also providing multiple environmental, economic and social benefits. However, the location of projects is often determined according to a single potential benefit rather than a set of benefits. Furthermore, while UGI is recognized as a successful strategy to support resilience in many cities around the world, it has not been implemented in Uruguay. This study develops a model to identify priority areas in need of green infrastructure in Montevideo, Uruguay. The GIS-based model, termed the “Green Infrastructure Suitability Model” (GISM) is based on a multi-criteria decision analysis approach and is similar in structure to land suitability analysis. The model considers a range of socioeconomic, biophysical and environmental factors to prioritize the need for UGI across the case-study region. Resulting suitability maps identify areas for multifunctional UGI localization in places where benefits can be maximized. The GISM has potential as a tool to support future planning for multifunctional UGI.