Abstract In this paper, we present a new methodology of clothing engineering construction for the medical application. Project “BIOAKOD” intends to propose clothing solutions for elderly people with dermatological defects. This purpose requires a particular concept of clothing because of the additional functionality expected in the clothing. It means that the proposed clothing needs to cover a human body in an aesthetic way and gives comfort of use it, and it should also bring an adding value in health treatment of people with dermatosis (psoriasis)..