Published in
American Physiological Society, AJP - Endocrinology and Metabolism, 1(320), p. E19-E29, 2021
DOI: 10.1152/ajpendo.00211.2020
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Estetrol prevents Western diet–induced obesity and atheroma independently of hepatic estrogen receptor α
Journal article published in 2021 by
Mélissa Buscato,
Morgane Davezac 
,
Rana Zahreddine,
Marine Adlanmerini,
Raphaël Métivier,
Marianne Fillet,
Gael Cobraiville,
Cedric Moro ,
Jean-Michel Foidart,
Françoise Lenfant,
Pierre Gourdy,
Jean-François Arnal ,
Coralie Fontaine
,
Rana Zahreddine,
Marine Adlanmerini,
Raphaël Métivier,
Marianne Fillet,
Gael Cobraiville,
Cedric Moro ,
Jean-Michel Foidart,
Françoise Lenfant,
Pierre Gourdy,
Jean-François Arnal ,
Coralie Fontaine
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Abstract
Estetrol prevents obesity, steatosis, and atherosclerosis in mice fed a Western diet. Hepatic ERα is necessary for the prevention of steatosis, but not of obesity and atherosclerosis